Gunn S, Reveles X, Weldon K, Barrera A, Ishaque M, Taylor D, McCaskill C, Kim J, Shah R, Mohammed M, Barry T, Kaiser B, Patnaik A, Tolcher A.
J Ovarian Res. 2013 Jan 4;6(1):2. doi: 10.1186/1757-2215-6-2.
Deshpande AM, Akunowicz JD, Reveles XT, Patel BB, Saria EA, Gorlick RG, Naylor SL, Leach RJ, Hansen MF.
Oncogene. 2007 Mar 15;26(12):1714-22. Epub 2006 Sep 25.
Vijayakumar S, Hall DC, Reveles XT, Troyer DA, Thompson IM, Garcia D, Xiang R, Leach RJ, Johnson-Pais TL, Naylor SL.
Cancer Res. 2006 Apr 15;66(8):4055-64.
Gunn SR, Reveles XT, Hamlington JD, Sadkowski LC, Johnson-Pais TL, Jorgensen JH.
J Clin Microbiol. 2006 Mar;44(3):1175-7.
Vaurs-Barriere C, Bonnet-Dupeyron MN, Combes P, Gauthier-Barichard F, Reveles XT, Schiffmann R, Bertini E, Rodriguez D, Vago P, Armour JA, Saugier-Veber P, Frebourg T, Leach RJ, Boespflug-Tanguy O.
Ann Hum Genet. 2006 Jan;70(Pt 1):66-77.
Chromosome 18 suppresses prostate cancer metastases.
Padalecki SS, Weldon KS, Reveles XT, Buller CL, Grubbs B, Cui Y, Yin JJ, Hall DC, Hummer BT, Weissman BE, Dallas M, Guise TA, Leach RJ, Johnson-Pais TL.
Urol Oncol. 2003 Sep-Oct;21(5):366-73.
Gunn SR, Mohammed M, Reveles XT, Viskochil DH, Palumbos JC, Johnson-Pais TL, Hale DE, Lancaster JL, Hardies LJ, Boespflug-Tanguy O, Cody JD, Leach RJ.
Am J Med Genet A. 2003 Jul 1;120A(1):127-35.
Regions of allelic imbalance in the distal portion of chromosome 12q in gastric cancer.
Schneider BG, Rha SY, Chung HC, Bravo JC, Mera R, Torres JC, Plaisance KT Jr, Schlegel R, McBride CM, Reveles XT, Leach RJ.
Mol Pathol. 2003 Jun;56(3):141-9.
Molecular characterization of 18p deletions: evidence for a breakpoint cluster.
Schaub RL, Reveles XT, Baillargeon J, Leach RJ, Cody JD.
Genet Med. 2002 Jan-Feb;4(1):15-9.
Genetic mapping of a novel X-linked recessive colobomatous microphthalmia.
Lehman DM, Sponsel WE, Stratton RF, Mensah J, Macdonald JC, Johnson-Pais TL, Coon H, Reveles XT, Cody JD, Leach RJ.
Am J Med Genet. 2001 Jun 15;101(2):114-9.
Haplosufficiency of the melancortin-4 receptor gene in individuals with deletions of 18q.
Cody JD, Reveles XT, Hale DE, Lehman D, Coon H, Leach RJ.
Hum Genet. 1999 Nov;105(5):424-7.
DuPont BR, Hu CC, Reveles X, Simmer JP.
Cytogenet Cell Genet. 1999;86(3-4):212-3. No abstract available.
The paper presents an efficient and effective method to analyze sputum on a flow cytometric platform, allowing for the development of high-throughput diagnostic tests for lung cancer and other lung diseases.
The poster presents the novel mechanism by which the porphyrin TCPP, which is used in bioAffinity Technologies’ non-invasive test for the early detection of lung cancer, is incorporated into cancer cells. These discoveries have furthered our understanding of TCPP for use in diagnostics including the Company’s first product, CyPath® Lung, a flow cytometry test used to diagnose lung cancer at early stage.
The presentation explains bioAffinity Technologies’ discovery of a fundamental vulnerability of cancer opens the way to new therapies that kill cancer without harm to normal tissue. In particular, bioAffinity’s research shows how the Company has designed and used siRNAs to kill multiple cancers at the cellular level including prostate, lung, breast, brain and skin cancers without harm to normal cells.