Publications

Clinical Trials and Research Studies

Early Detection of Lung Cancer with Meso Tetra (4-Carboxyphenyl) Porphine (TCPP)-Labeled Sputum, Journal of Thoracic Oncology, September, 2015

The clinical study demonstrated 81% accuracy in detecting cancer from sputum samples collected from participants in two cohorts. The high-risk cohort included military veterans who had smoked at least 20 pack-years.

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Internal Validation Research Trial

In this internal study, the assay revealed 100% specificity and 100% sensitivity.
Researchers investigated meso Tetra (4-Carboxyphenyl) Porphine (TCPP), a porphyrin that can label cancer cells.

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Research at Los Alamos National Laboratory and St Mary’s Hospital

St. Mary’s Hospital and the Isotope and Nuclear Chemistry Division of the Medical Radioisotopes Research Program at Los Alamos National Laboratory conducted preliminary studies from 1988 to 1992 researching porphyrins that led to more specific research into 10,15,20-tetrakis (4-carboxyphenyl) porphine (TCPP) and its ability to detect lung cancer by labeling cancer cells in sputum.

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